SCHEMBL2714248

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2714811	0.90	MAP4K1 (0.39)	GSK3BJAK1MAP4K1ABL1
	SCHEMBL2716860	0.89	CNR2 (0.35)	GSK3AGSK3BJAK1JAK2MAP4K1
	SCHEMBL2719013	0.89	MAP4K1 (0.39)	GSK3AGSK3BJAK1MAPK1MAP4K1
	SCHEMBL2716113	0.88	GSK3B (0.40)	GSK3AGSK3BJAK1IDH1MAP4K1
	SCHEMBL2716154	0.88	GSK3B (0.47)	TYK2KLKB1GSK3AGSK3BIDH1
	SCHEMBL2714154	0.87	SCN9A (0.37)	TYK2KLKB1MALT1ABL1
	SCHEMBL2713815	0.87	TYK2 (0.40)	TYK2JAK1MALT1MAPK1RPS6KA1
	SCHEMBL2715979	0.85	ACACB (0.41)	TYK2IDH1ABL1
	SCHEMBL2714791	0.84	GSK3B (0.52)	TYK2GSK3AGSK3B
	SCHEMBL2717492	0.82	ABL1 (0.39)	TYK2JAK1IDH1BRAFKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.