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SCHEMBL27148382

SCHEMBL27148382

CCCCCCCCCCCCNCCCCCCNC(=O)C(CCC(=O)OC(C)(C)C)NC(=O)C(CCC(=O)OC(C)(C)C)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 6/20 0.51
▸ KMT2A Q03164 2/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ TNF P01375 2/20 0.43
▸ PTPN1 P18031 1/20 0.42
▸ SIRT2 Q8IXJ6 2/20 0.42
▸ SIRT1 Q96EB6 2/20 0.42
▸ SIRT3 Q9NTG7 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12356377 0.96 TLR2 (0.54) TLR2KMT2AMEN1ALDH1A1HPGD
SCHEMBL30019942 0.94 TLR2 (0.52) TLR2KMT2AMEN1ALDH1A1HPGD
SCHEMBL27248275 0.94 TLR2 (0.52) TLR2KMT2AMEN1ALDH1A1HPGD
SCHEMBL30020633 0.92 TLR2 (0.53) TLR2KMT2AMEN1ALDH1A1HPGD
SCHEMBL30019865 0.90 TLR2 (0.50) TLR2KMT2AMEN1ALDH1A1HPGD
SCHEMBL30020706 0.90 TLR2 (0.50) TLR2KMT2AMEN1ALDH1A1HPGD
SCHEMBL2357935 0.87 KMT2A (0.52) TLR2KMT2ATNF
SCHEMBL2357936 0.87 KMT2A (0.52) TLR2KMT2ATNF
SCHEMBL5493441 0.87 KMT2A (0.52) TLR2KMT2ATNF
SCHEMBL16328803 0.87 TLR2 (0.59) TLR2KMT2ASIRT2SIRT1SIRT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4326741-A1 CYCLOPOLYPHOSPHAZENES, RELATED METHODS OF PREPARATION AND METHODS OF USE University of Saskatchewan (CA) 2024-02-28 — — EP disclosed
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