SCHEMBL2714973

SCHEMBL2714973

Fc1ccccc1COCc1ccccc1F

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.67
TAAR1 Q96RJ0 3/20 0.52
ALDH1A1 P00352 4/20 0.52
MAOB P27338 5/20 0.50
MCL1 Q07820 1/20 0.47
PARP15 Q460N3 2/20 0.46
PARP10 Q53GL7 2/20 0.46
PARP14 Q460N5 1/20 0.46
LMNA P02545 2/20 0.44
USP2 O75604 1/20 0.44
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP12 P39900 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42
TP53 P04637 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31065556 1.00 IDO1 (0.67) IDO1TAAR1ALDH1A1MAOBMCL1
SCHEMBL3156632 0.86 IDO1 (0.57) IDO1TAAR1ALDH1A1MAOBMCL1
SCHEMBL12874173 0.86 IDO1 (0.57) IDO1TAAR1ALDH1A1MAOBMCL1
SCHEMBL10458290 0.84 IDO1 (0.55) IDO1TAAR1ALDH1A1MAOBMCL1
SCHEMBL6232816 0.83 IDO1 (0.53) IDO1TAAR1ALDH1A1MAOBMCL1
SCHEMBL8744312 0.83 IDO1 (0.53) IDO1TAAR1ALDH1A1MAOBMCL1
SCHEMBL1984467 0.83 IDO1 (0.53) IDO1TAAR1ALDH1A1MAOBMCL1
SCHEMBL10847719 0.83 IDO1 (0.53) IDO1TAAR1ALDH1A1MAOBMCL1
SCHEMBL17757996 0.81 IDO1 (0.52) IDO1TAAR1ALDH1A1MAOBMCL1
SCHEMBL8744311 0.81 IDO1 (0.68) IDO1TAAR1ALDH1A1MAOBMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945859-B Process synthesis of o-fluorophenol 内蒙古源宏精细化工有限公司 2024-06-18 CN claimed
CN-117945859-A Process synthesis of o-fluorophenol 内蒙古源宏精细化工有限公司 2024-04-30 CN claimed
CN-117497858-A Electrolyte and lithium ion battery 蜂巢能源科技股份有限公司 2024-02-02 CN claimed
CN-107686465-B Preparation method of deracoxib 东北农业大学 2020-10-27 CN claimed
JP-9031005-A None JP disclosed
CN-117945859-B Process synthesis of o-fluorophenol 内蒙古源宏精细化工有限公司 2024-06-18 CN disclosed
CN-117945859-A Process synthesis of o-fluorophenol 内蒙古源宏精细化工有限公司 2024-04-30 CN disclosed
CN-117497858-A Electrolyte and lithium ion battery 蜂巢能源科技股份有限公司 2024-02-02 CN disclosed
CN-115974900-A Polycyclic aromatic compound, polymer compound, composition, material, light-emitting element, display device, and lighting device 学校法人关西学院 2023-04-18 CN disclosed
CN-110498770-B Method for preparing intermediate of oxaagolide 上海医药工业研究院 2023-02-17 CN disclosed
CN-115368218-A Method for preparing 4-diaryl methyl substituted phenol compound 湖南理工学院 2022-11-22 CN disclosed
CN-114989198-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2022-09-02 CN disclosed
WO-2007042239-A1 PROLINAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS GLAXO GROUP LIMITED (GB) 2007-04-19 WO disclosed
WO-2007042240-A1 QUATERNARY ALPHA-AMINOCARBOXAMIDE DERIVATIVES AS MODULATORS OF VOLTAGE-GATED SODIUM CHANNELS GLAXO GROUP LIMITED (GB) 2007-04-19 WO disclosed
WO-2007042250-A1 PROLINAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS GLAXO GROUP LIMITED (GB) 2007-04-19 WO disclosed
CN-1085649-C Fluorobenzylic ether derivatives ROLIC AG (CH) 2002-05-29 CN disclosed
US-5888423-A Fluorobenzyl ether derivatives ROLIC AG (CH) 1999-03-30 US disclosed
US-5888423-A Fluorobenzyl ether derivatives ROLIC AG (CH) 1999-03-30 US disclosed
US-5888423-A Fluorobenzyl ether derivatives ROLIC AG (CH) 1999-03-30 US disclosed
JP-H0931005-A FLUOROBENZYL ETHER DERIVATIVE ROLIC AG 1997-02-04 JP disclosed