Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27135175 | 1.00 | ABL1 (0.41) | ABL1MAP4K1PIK3C3 | |
| SCHEMBL27136831 | 0.91 | ABL1 (0.43) | ABL1MAP4K1PIK3C3 | |
| SCHEMBL30780192 | 0.90 | ABL1 (0.43) | ABL1MAP4K1 | |
| SCHEMBL27135174 | 0.90 | ABL1 (0.43) | ABL1MAP4K1 | |
| SCHEMBL30885042 | 0.85 | ABL1 (0.41) | ABL1MAP4K1 | |
| SCHEMBL27135102 | 0.83 | ABL1 (0.49) | ABL1MAP4K1PIK3C3 | |
| SCHEMBL30780108 | 0.83 | ABL1 (0.49) | ABL1MAP4K1PIK3C3 | |
| SCHEMBL27138339 | 0.83 | ABL1 (0.49) | ABL1MAP4K1PIK3C3 | |
| SCHEMBL27135105 | 0.83 | ABL1 (0.49) | ABL1MAP4K1PIK3C3 | |
| SCHEMBL30780257 | 0.81 | ABL1 (0.43) | ABL1MAP4K1PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044713-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-02-29 | — | — | WO | disclosed |