SCHEMBL2715517

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2713374	0.93	GSK3B (0.51)	GSK3BMAPTSCN9AL3MBTL1SMN1; SMN2
	SCHEMBL2718292	0.91	GSK3B (0.45)	GSK3BMAPTSCN9AALDH1A1NPC1
	SCHEMBL2716106	0.90	SCN9A (0.47)	GSK3BMAPTSCN9AALDH1A1NPC1
	SCHEMBL2716491	0.90	GSK3B (0.52)	GSK3BMAPTSCN9AALDH1A1L3MBTL1
	SCHEMBL2714570	0.90	GSK3B (0.61)	GSK3BMAPTSCN9AL3MBTL1SMN1; SMN2
	SCHEMBL2714900	0.88	GSK3B (0.49)	GSK3BMAPTSCN9AL3MBTL1SMN1; SMN2
	SCHEMBL2714793	0.87	GSK3B (0.42)	GSK3BMAPTSCN9AALDH1A1NPC1
	SCHEMBL2715806	0.87	GSK3B (0.50)	GSK3BMAPTGSK3A
	SCHEMBL2717705	0.84	GSK3B (0.47)	GSK3BMAPTSCN9AALDH1A1NPC1
	SCHEMBL2713412	0.83	SCN9A (0.48)	GSK3BMAPTSCN9ANPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.