Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | CHUK | O15111 | 2/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29912832 | 1.00 | IKBKB (0.47) | IKBKBCHUKSSTR4PTPN11ACP1 | |
| SCHEMBL29912834 | 1.00 | IKBKB (0.47) | IKBKBCHUKSSTR4PTPN11ACP1 | |
| SCHEMBL30785460 | 1.00 | IKBKB (0.47) | IKBKBCHUKSSTR4PTPN11ACP1 | |
| Hydrochloric Acid SCHEMBL27158040 | 0.99 | IKBKB (0.46) | IKBKBCHUKSSTR4PTPN11ACP1 | |
| Hydrochloric Acid SCHEMBL27158015 | 0.99 | IKBKB (0.46) | IKBKBCHUKSSTR4PTPN11ACP1 | |
| Hydrochloric Acid SCHEMBL29912916 | 0.99 | IKBKB (0.46) | IKBKBCHUKSSTR4PTPN11ACP1 | |
| Hydrochloric Acid SCHEMBL29912884 | 0.99 | IKBKB (0.46) | IKBKBCHUKSSTR4PTPN11ACP1 | |
| SCHEMBL30785491 | 0.84 | SSTR4 (0.47) | IKBKBCHUKSSTR4RBP4 | |
| SCHEMBL29202380 | 0.84 | SSTR4 (0.47) | IKBKBCHUKSSTR4RBP4 | |
| Hydrochloric Acid SCHEMBL29913132 | 0.83 | SSTR4 (0.47) | IKBKBCHUKSSTR4RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751114-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |