SCHEMBL2716281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715920	0.92	SCN9A (0.47)	SCN9AMAPTGSK3BSCN5ACYP3A4
	SCHEMBL2715896	0.91	SCN9A (0.50)	SCN9AMAPTGSK3BPRKD3MAPK8
	SCHEMBL2715666	0.91	SCN9A (0.48)	SCN9AMAPTGSK3BKCNH2PRKD3
	SCHEMBL2716105	0.90	SCN9A (0.46)	SCN9AMAPTGSK3BSCN5ACYP3A4
	SCHEMBL2716989	0.89	SCN9A (0.45)	SCN9AGSK3BSCN5AGCKKCNH2
	SCHEMBL2714442	0.89	SCN9A (0.63)	SCN9AMAPTGSK3B
	SCHEMBL2717389	0.89	SCN9A (0.46)	SCN9AMAPTGSK3B
	SCHEMBL2715476	0.87	SCN9A (0.45)	SCN9AMAPTGSK3BSCN5AGCK
	SCHEMBL2715485	0.86	MAPT (0.59)	SCN9AMAPTGSK3BSCN5ACYP3A4
	SCHEMBL2715100	0.86	SCN9A (0.44)	SCN9AMAPTGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.