SCHEMBL2716285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2713412	0.91	SCN9A (0.48)	SCN9AGSK3BMAPTJAK2JAK1
	SCHEMBL2716465	0.91	SCN9A (0.61)	SCN9AGSK3BMAPTTYK2HTT
	SCHEMBL18266475	0.90	SCN9A (0.50)	SCN9AGSK3BMAPTKLKB1MAP4K1
	SCHEMBL2714090	0.90	GSK3B (0.48)	SCN9AGSK3BMAPTKLKB1MAP4K1
	SCHEMBL16234578	0.89	SCN9A (0.49)	SCN9AGSK3BMAPTMAP4K1L3MBTL1
	SCHEMBL2716106	0.89	SCN9A (0.47)	SCN9AGSK3BMAPTL3MBTL1ALDH1A1
	SCHEMBL2716491	0.89	GSK3B (0.52)	SCN9AGSK3BMAPTL3MBTL1ACHE
	SCHEMBL2714791	0.88	GSK3B (0.52)	SCN9AGSK3BMAPTTYK2GSK3A
	SCHEMBL2716945	0.87	SCN9A (0.54)	SCN9AGSK3BMAPTKLKB1MAP4K1
	SCHEMBL2718458	0.86	SCN9A (0.50)	SCN9AGSK3BMAPTKLKB1MAP4K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.