SCHEMBL2716501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2713376	0.93	SCN9A (0.52)	SCN9AMAPTGSK3BALDH1A1HTT
	SCHEMBL2715554	0.91	SCN9A (0.42)	SCN9AMAPTGSK3BALDH1A1HTT
	SCHEMBL2717159	0.89	SCN9A (0.44)	SCN9AMAPTGSK3BALDH1A1CHRNB2
	SCHEMBL2718458	0.89	SCN9A (0.50)	SCN9AMAPTGSK3BALDH1A1HTT
	SCHEMBL2716797	0.87	SCN9A (0.48)	SCN9AMAPTGSK3BRIPK1
	SCHEMBL2716491	0.86	GSK3B (0.52)	SCN9AMAPTGSK3BALDH1A1HTT
	SCHEMBL2714871	0.86	SCN9A (0.39)	SCN9AGSK3BRIPK1
	SCHEMBL2718745	0.85	SCN9A (0.52)	SCN9AMAPTGSK3BHTTPRKD3
	SCHEMBL2717417	0.84	SCN9A (0.61)	SCN9AMAPTGSK3BHTTKDM4E
	SCHEMBL2715779	0.84	SCN9A (0.51)	SCN9AMAPTGSK3BALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.