Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27166213 | 0.88 | BCHE (0.41) | PIK3CACYSLTR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL25170150 | 0.86 | PIK3CA (0.44) | PIK3CACYSLTR1KDM4EPIK3CBPOLB | |
| SCHEMBL27166211 | 0.85 | PIK3CA (0.43) | PIK3CACYSLTR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL23887022 | 0.85 | PIK3CA (0.67) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL23887216 | 0.83 | PIK3CA (0.49) | PIK3CAALDH1A1HPGDHSD17B10PIK3CB | |
| SCHEMBL23887153 | 0.83 | PIK3CA (0.49) | PIK3CAALDH1A1HPGDHSD17B10PIK3CB | |
| SCHEMBL25175997 | 0.83 | PIK3CA (0.42) | PIK3CACYSLTR1KDM4EPIK3CBPOLB | |
| SCHEMBL23887119 | 0.82 | PIK3CA (0.65) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL23887339 | 0.82 | PIK3CA (0.49) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL23887072 | 0.82 | PIK3CA (0.63) | PIK3CAPIK3CBMTORPRKDCPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4333984-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2024-03-13 | — | — | EP | disclosed |