Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 12/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 5/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26925883 | 0.91 | CRBN (0.44) | DDB1CRBNIRAK4 | |
| SCHEMBL21069509 | 0.90 | DDB1 (0.60) | DDB1CRBNIRAK4EGFRGSK3B | |
| SCHEMBL29991552 | 0.90 | CRBN (0.48) | DDB1CRBNIRAK4EGFRGSK3B | |
| SCHEMBL22835718 | 0.89 | CRBN (0.50) | DDB1CRBNIRAK4 | |
| SCHEMBL21996944 | 0.88 | DDB1 (0.51) | DDB1CRBNIRAK4EGFRGSK3B | |
| SCHEMBL22526027 | 0.87 | DDB1 (0.52) | DDB1CRBNIRAK4EGFRGSK3B | |
| SCHEMBL21071063 | 0.86 | DDB1 (0.43) | DDB1CRBNIRAK4EGFR | |
| SCHEMBL21071081 | 0.86 | DDB1 (0.55) | DDB1CRBNIRAK4EGFRGSK3B | |
| SCHEMBL21997229 | 0.86 | DDB1 (0.49) | DDB1CRBNIRAK4EGFRGSK3B | |
| SCHEMBL21070743 | 0.85 | DDB1 (0.50) | DDB1CRBNIRAK4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |