Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 11/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 3/20 | 0.38 |
| ▸ | STAT3 | P40763 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20840366 | 1.00 | DDB1 (0.51) | DDB1CRBNGSK3BTRIM24STAT3 | |
| SCHEMBL20840336 | 1.00 | DDB1 (0.51) | DDB1CRBNGSK3BTRIM24STAT3 | |
| SCHEMBL21069333 | 0.90 | DDB1 (0.62) | DDB1CRBNGSK3BTRIM24STAT3 | |
| SCHEMBL30299006 | 0.90 | DDB1 (0.62) | DDB1CRBNGSK3BTRIM24STAT3 | |
| SCHEMBL20845736 | 0.90 | DDB1 (0.62) | DDB1CRBNGSK3BTRIM24STAT3 | |
| SCHEMBL20850758 | 0.90 | DDB1 (0.62) | DDB1CRBNGSK3BTRIM24STAT3 | |
| SCHEMBL22502694 | 0.89 | DDB1 (0.51) | DDB1CRBNGSK3BTRIM24 | |
| SCHEMBL27166369 | 0.89 | DDB1 (0.51) | DDB1CRBNGSK3BTRIM24STAT3 | |
| SCHEMBL29990961 | 0.89 | DDB1 (0.51) | DDB1CRBNGSK3BTRIM24STAT3 | |
| SCHEMBL27166593 | 0.89 | DDB1 (0.51) | DDB1CRBNGSK3BTRIM24STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |