Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27166518 | 0.95 | DDB1 (0.44) | DDB1CRBNCCR5OPRM1OGFRL1 | |
| SCHEMBL23536296 | 0.92 | DDB1 (0.48) | DDB1CRBNCCR5 | |
| SCHEMBL26101564 | 0.92 | DDB1 (0.47) | DDB1CRBNCCR5OPRM1OGFRL1 | |
| SCHEMBL22835611 | 0.92 | DDB1 (0.47) | DDB1CRBNCCR5 | |
| SCHEMBL29751290 | 0.92 | DDB1 (0.48) | DDB1CRBNCCR5 | |
| SCHEMBL31727438 | 0.92 | DDB1 (0.48) | DDB1CRBNCCR5 | |
| SCHEMBL24607422 | 0.92 | DDB1 (0.48) | DDB1CRBNCCR5 | |
| SCHEMBL26100345 | 0.91 | DDB1 (0.46) | DDB1CRBNCCR5OPRM1OGFRL1 | |
| SCHEMBL26100587 | 0.89 | DDB1 (0.44) | DDB1CRBNCCR5OPRM1OGFRL1 | |
| SCHEMBL29751154 | 0.88 | DDB1 (0.52) | DDB1CRBNOPRM1OGFRL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022236058-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |