Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386092 | 0.89 | TRPV1 (0.47) | TRPV1NPSR1KDM4EMAPTHSD17B10 | |
| SCHEMBL2385038 | 0.88 | TRPV1 (0.48) | TRPV1NPSR1KDM4EMAPTHSD17B10 | |
| SCHEMBL2383625 | 0.87 | TRPV1 (0.51) | TRPV1NPSR1HSD17B10 | |
| SCHEMBL2384368 | 0.86 | TRPV1 (0.45) | TRPV1NPSR1MAPTHSD17B10NR2E1 | |
| SCHEMBL2385067 | 0.85 | MAPT (0.45) | TRPV1NPSR1KDM4EMAPTPDGFRB | |
| SCHEMBL2385265 | 0.84 | TRPV1 (0.45) | TRPV1NPSR1KDM4EMAPTHSD17B10 | |
| SCHEMBL2384448 | 0.83 | TRPV1 (0.46) | TRPV1NPSR1KDM4EMAPTHSD17B10 | |
| SCHEMBL2383249 | 0.83 | TRPV1 (0.55) | TRPV1NPSR1KDM4EMAPTHSD17B10 | |
| SCHEMBL2384340 | 0.83 | MAPT (0.45) | TRPV1NPSR1KDM4EMAPTHSD17B10 | |
| SCHEMBL2383828 | 0.82 | TRPV1 (0.48) | TRPV1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |