SCHEMBL2717028

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18266560	0.93	MAPT (0.49)	MAPTGSK3BSCN9AKCNB1PPARG
	SCHEMBL18266628	0.92	MAPT (0.50)	MAPTGSK3BSCN9AKCNB1PPARG
	SCHEMBL2715370	0.91	MAPT (0.51)	MAPTGSK3BSCN9AKCNB1SCN3A
	SCHEMBL2713838	0.90	SCN9A (0.55)	MAPTGSK3BSCN9AKCNB1SCN3A
	SCHEMBL2715633	0.90	GSK3B (0.61)	MAPTGSK3BSCN9AKCNB1ROS1
	SCHEMBL2718283	0.89	CYP3A4 (0.45)	SCN9ASCN3AROCK2PPARGPPARD
	SCHEMBL2715551	0.89	MAPT (0.51)	MAPTGSK3BSCN9AKCNB1SCN3A
	SCHEMBL2715091	0.88	SCN3A (0.43)	SCN9ASCN3AROCK2PPARGPPARD
	SCHEMBL2714516	0.88	SCN9A (0.49)	SCN9AKCNB1ROCK2PPARGPPARD
	SCHEMBL2717172	0.87	MAPT (0.61)	MAPTGSK3BSCN9AKCNB1ROS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.