Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 20/20 | 0.65 |
| ▸ | KAT6A | Q92794 | 20/20 | 0.65 |
| ▸ | KAT6B | Q8WYB5 | 10/20 | 0.65 |
| ▸ | KAT5 | Q92993 | 10/20 | 0.65 |
| ▸ | KAT8 | Q9H7Z6 | 10/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360825 | 1.00 | KAT7 (0.65) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25562556 | 0.95 | KAT7 (0.72) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30360829 | 0.95 | KAT7 (0.72) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25562429 | 0.90 | KAT7 (0.68) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25562694 | 0.90 | KAT7 (0.67) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30360851 | 0.90 | KAT7 (0.67) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30360828 | 0.88 | KAT7 (0.65) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25565845 | 0.88 | KAT7 (0.65) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30360832 | 0.88 | KAT7 (0.65) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL27184168 | 0.88 | KAT7 (0.65) | KAT7KAT6AKAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12091406-B2 | Lysine acetyltransferase 6A (KAT6A) inhibitors and uses thereof | INSILICO MEDICINE IP LIMITED (HK) | 2024-09-17 | — | — | US | disclosed |
| US-20240150374-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (HK) | 2024-05-09 | — | — | US | disclosed |
| US-20240109880-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (HK) | 2024-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12091406-B2 | Lysine acetyltransferase 6A (KAT6A) inhibitors and uses thereof | KAT6A, KAT2A, KAT6B | KAT7 5/4885KAT6A 1/4885KAT6B 3/4885 |
| US-20240150374-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | KAT6A, KAT2A, KAT6B | KAT7 5/4885KAT6A 1/4885KAT6B 3/4885 |
| US-20240109880-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | KAT6A, KAT2A, KAT6B | KAT7 5/4885KAT6A 1/4885KAT6B 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.