Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.59 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.50 |
| ▸ | HTR1F | P30939 | 12/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | HTR1D | P28221 | 4/20 | 0.46 |
| ▸ | HTR1B | P28222 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30863481 | 1.00 | HDAC1 (0.59) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL27195780 | 0.88 | HDAC1 (0.58) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL27195730 | 0.88 | HDAC1 (0.58) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL27195724 | 0.83 | HDAC1 (0.62) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL30863440 | 0.82 | HDAC3 (0.62) | HDAC3HDAC8 | |
| SCHEMBL27195699 | 0.82 | HDAC3 (0.62) | HDAC3HDAC8 | |
| SCHEMBL27195718 | 0.81 | HDAC1 (0.57) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL27195743 | 0.80 | HDAC6 (0.62) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL27195717 | 0.80 | HDAC1 (0.56) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL27195716 | 0.77 | HDAC1 (0.55) | HDAC1HDAC3HDAC2HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353712-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2024-04-17 | — | — | EP | claimed |
| EP-4353712-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2024-04-17 | — | — | EP | disclosed |