SCHEMBL27201034

SCHEMBL27201034

CCN(C)C=Nc1cc(C)c(C(OC)c2ccccc2)cc1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.34
ADRA2A P08913 3/20 0.34
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
ADRA2B P18089 2/20 0.34
CHRM3 P20309 2/20 0.34
SLC6A2 P23975 2/20 0.34
HRH2 P25021 2/20 0.34
HTR2A P28223 2/20 0.34
HTR2C P28335 2/20 0.34
SLC6A4 P31645 2/20 0.34
ADRA1A P35348 2/20 0.34
HRH1 P35367 2/20 0.34
OPRM1 P35372 2/20 0.34
DRD3 P35462 2/20 0.34
HTR2B P41595 2/20 0.34
HTR6 P50406 2/20 0.34
SLC6A3 Q01959 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21495736 0.88 ESR1 (0.36) CYP2D6ADRA2ACHRM2CHRM4CHRM5
SCHEMBL21495735 0.88 ESR1 (0.36) CYP2D6ADRA2ACHRM2CHRM4CHRM5
SCHEMBL21495253 0.88 CYP2D6 (0.35) CYP2D6ADRA2ACHRM2CHRM4CHRM5
SCHEMBL21495254 0.88 CYP2D6 (0.35) CYP2D6ADRA2ACHRM2CHRM4CHRM5
SCHEMBL21495441 0.85 CYP2C19 (0.31) CYP3A4CYP2C19CYP2C9
SCHEMBL21495440 0.85 CYP2C19 (0.31) CYP3A4CYP2C19CYP2C9
SCHEMBL2985090 0.81 AOC3 (0.30)
SCHEMBL2985087 0.81 AOC3 (0.30)
SCHEMBL21495454 0.81 AOC3 (0.33) LMNASMN1; SMN2
SCHEMBL21495452 0.81 AOC3 (0.33) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3525588-B1 4-SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE TO PROTECT CROPS BY FIGHTING UNDESIRED PHYTOPATHOGENIC MICOORGANISMS PI INDUSTRIES LTD (IN) 2024-04-24 EP claimed