Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.60 |
| ▸ | HPGDS | O60760 | 2/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.51 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29841499 | 1.00 | CRBN (0.60) | CRBNHPGDSDDB1BTKIKZF3 | |
| SCHEMBL24734969 | 0.88 | CRBN (0.54) | CRBNHPGDSDDB1BTKIKZF3 | |
| SCHEMBL29841424 | 0.88 | CRBN (0.54) | CRBNHPGDSDDB1BTKIKZF3 | |
| SCHEMBL22661369 | 0.87 | CRBN (0.65) | CRBNHPGDSDDB1BTKIKZF3 | |
| SCHEMBL30312927 | 0.87 | CRBN (0.65) | CRBNHPGDSDDB1BTKIKZF3 | |
| SCHEMBL22645447 | 0.85 | CRBN (0.55) | CRBNHPGDSDDB1BTKAR | |
| SCHEMBL25196629 | 0.84 | CRBN (0.61) | CRBNHPGDSDDB1BTKIKZF3 | |
| SCHEMBL22661317 | 0.83 | CRBN (0.57) | CRBNHPGDSDDB1BTKAR | |
| SCHEMBL20046280 | 0.82 | CRBN (0.63) | CRBNHPGDSDDB1BTKAR | |
| SCHEMBL29878029 | 0.82 | CRBN (0.63) | CRBNHPGDSDDB1BTKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132502-A1 | SUBSTITUTED PYRROLOPYRIMIDINE AND PYRAZOLOPYRIMIDINE AS BRUTON'S TYROSINE KINASE (BTK) DEGRADERS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132502-A1 | SUBSTITUTED PYRROLOPYRIMIDINE AND PYRAZOLOPYRIMIDINE AS BRUTON'S TYROSINE KINASE (BTK) DEGRADERS | BTK, LYN, SYK | CRBN 439/4885HPGDS 779/4885DDB1 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.