Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971394 | 1.00 | BTK (0.69) | BTK | |
| SCHEMBL29227454 | 0.91 | BTK (0.83) | BTK | |
| SCHEMBL31001145 | 0.90 | BTK (0.74) | BTK | |
| SCHEMBL27208355 | 0.90 | BTK (0.74) | BTK | |
| SCHEMBL30971395 | 0.89 | BTK (0.67) | BTK | |
| SCHEMBL27208488 | 0.89 | BTK (0.67) | BTK | |
| SCHEMBL29227461 | 0.88 | BTK (0.79) | BTK | |
| SCHEMBL20558418 | 0.87 | BTK (0.72) | BTK | |
| SCHEMBL30139743 | 0.87 | BTK (0.73) | BTK | |
| SCHEMBL27208417 | 0.87 | BTK (0.73) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4361153-A1 | NOVEL BIFUNCTIONAL HETEROCYCLIC COMPOUND HAVING BTK DEGRADATION FUNCTION VIA UBIQUITIN PROTEASOME PATHWAY, AND USE THEREOF | Korea Research Institute of Chemical Technology (KR) | 2024-05-01 | — | — | EP | disclosed |
| CN-117836299-A | Novel bifunctional heterocyclic compounds with Bruton tyrosine kinase decomposition via ubiquitin proteasome pathway and uses thereof | 韩国化学研究院 | 2024-04-05 | — | — | CN | disclosed |