SCHEMBL27217171

SCHEMBL27217171

Cn1cc(-c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)nc1C1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 12/20 0.54
▸ CRBN Q96SW2 7/20 0.53
▸ IKZF1 Q13422 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27328800 0.95 CRBN (0.56) IKZF2CRBNIKZF1
SCHEMBL27217075 0.93 CRBN (0.53) IKZF2CRBNIKZF1
SCHEMBL27217079 0.93 CRBN (0.53) IKZF2CRBNIKZF1
SCHEMBL27217003 0.91 CRBN (0.52) IKZF2CRBNIKZF1
SCHEMBL27217043 0.91 IKZF2 (0.53) IKZF2CRBNIKZF1
SCHEMBL27217052 0.91 CRBN (0.52) IKZF2CRBNIKZF1
SCHEMBL27217101 0.91 CRBN (0.51) IKZF2CRBNIKZF1
SCHEMBL27217229 0.89 CRBN (0.49) IKZF2CRBNIKZF1
SCHEMBL27217230 0.89 CRBN (0.49) IKZF2CRBNIKZF1
SCHEMBL27313009 0.89 IKZF2 (0.52) IKZF2CRBNIKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584259-A1 CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS Innovo Therapeutics, Inc. (US) 2025-07-16 — — EP disclosed
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. 2024-05-16 — — US disclosed
WO-2024054832-A1 CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-03-14 — — WO disclosed
WO-2024054832-A1 CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-03-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS CKS1B, CKS2, MARK1 IKZF2 4089/4885CRBN 764/4885IKZF1 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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