Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.76 |
| ▸ | CLK1 | P49759 | 5/20 | 0.76 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.76 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.76 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.76 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.76 |
| ▸ | PIM1 | P11309 | 3/20 | 0.76 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.76 |
| ▸ | MTOR | P42345 | 2/20 | 0.76 |
| ▸ | CLK2 | P49760 | 2/20 | 0.76 |
| ▸ | GAK | O14976 | 1/20 | 0.76 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.76 |
| ▸ | STK10 | O94804 | 1/20 | 0.76 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.76 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.76 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.76 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.76 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.76 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.76 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739026 | 1.00 | PIK3CA (0.76) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD | |
| Gsk-1059615 SCHEMBL1805561 | 0.86 | PIK3CA (1.00) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD | |
| Gsk-1059615 SCHEMBL1805557 | 0.86 | PIK3CA (1.00) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD | |
| Gsk-1059615 SCHEMBL29381321 | 0.86 | PIK3CA (1.00) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD | |
| Gsk-1059615 SCHEMBL1805560 | 0.86 | PIK3CA (1.00) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD | |
| Gsk-1059615 SCHEMBL29351551 | 0.86 | PIK3CA (1.00) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD | |
| SCHEMBL1808883 | 0.77 | CLK1 (0.69) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD | |
| SCHEMBL30827802 | 0.76 | PIK3CA (0.60) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD | |
| SCHEMBL732106 | 0.76 | PIK3CA (0.60) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD | |
| SCHEMBL729541 | 0.75 | PIK3CA (0.77) | PIK3CACLK1DYRK1ACSNK2A2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166759-A1 | COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPEUTIC AGENTS AND METHODS OF USING THE SAME | ANGIEX, INC. | 2024-05-23 | — | — | US | disclosed |
| CN-107667092-B | Formylated N-heterocyclic derivatives as FGFR4 inhibitors | 诺华股份有限公司 | 2021-05-28 | — | — | CN | disclosed |