SCHEMBL27233333

SCHEMBL27233333

CCOC(=O)COc1ccc(SCn2ncn(-c3ccc(C(F)(F)F)cc3)c2=O)cc1C

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.60
PPARA Q07869 10/20 0.60
PPARG P37231 7/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27233412 0.97 PPARD (0.58) PPARDPPARAPPARG
SCHEMBL27233392 0.92 PPARD (0.55) PPARDPPARAPPARG
SCHEMBL27233512 0.91 PPARD (0.54) PPARDPPARAPPARG
SCHEMBL27233400 0.91 PPARD (0.49) PPARDPPARAPPARG
SCHEMBL27233504 0.90 PPARD (0.66) PPARDPPARAPPARG
SCHEMBL27233441 0.89 PPARD (0.49) PPARDPPARAPPARG
SCHEMBL27233451 0.89 PPARD (0.47) PPARDPPARAPPARG
SCHEMBL27233431 0.89 PPARD (0.47) PPARDPPARAPPARG
SCHEMBL27233332 0.89 PPARD (0.47) PPARDPPARAPPARG
SCHEMBL27233511 0.88 PPARD (0.56) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4378931-A1 TRIAZOLONE COMPOUND AND MEDICINAL USE THEREOF Harbin Medisan Pharmaceutical Co., LTD. (CN) 2024-06-05 EP claimed
US-20250188044-A1 TRIAZOLONE COMPOUND, PHARMACEUTICAL USE THEREOF AND PHARMACEUTICAL COMPOSITION HARBIN MEDISAN PHARMACEUTICAL CO., LTD. (CN) 2025-06-12 US disclosed
EP-4378931-A1 TRIAZOLONE COMPOUND AND MEDICINAL USE THEREOF Harbin Medisan Pharmaceutical Co., LTD. (CN) 2024-06-05 EP disclosed
CN-114853686-B Triazolone compound and medical application thereof 中国药科大学 2023-06-20 CN disclosed
CN-114853686-A Triazole ketone compound and medical application thereof 中国药科大学 2022-08-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188044-A1 TRIAZOLONE COMPOUND, PHARMACEUTICAL USE THEREOF AND PHARMACEUTICAL COMPOSITION PPARD, PPARA, PPARG PPARD 1/4885PPARA 2/4885PPARG 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.