Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130027 | 1.00 | TSHR (0.44) | TSHRABCC4MAPTLPAR3LPAR2 | |
| SCHEMBL2014805 | 1.00 | TSHR (0.44) | TSHRABCC4MAPTLPAR3LPAR2 | |
| SCHEMBL18789413 | 1.00 | TSHR (0.44) | TSHRABCC4MAPTLPAR3LPAR2 | |
| SCHEMBL3009250 | 1.00 | TSHR (0.44) | TSHRABCC4MAPTLPAR3LPAR2 | |
| SCHEMBL747368 | 0.97 | TSHR (0.40) | TSHRABCC4MAPTLPAR3LPAR2 | |
| SCHEMBL1280006 | 0.92 | — | — | |
| SCHEMBL1795931 | 0.89 | TSHR (0.64) | TSHRALDH1A1 | |
| SCHEMBL1798619 | 0.88 | TSHR (0.61) | TSHRALDH1A1 | |
| SCHEMBL1793252 | 0.88 | TSHR (0.61) | TSHRALDH1A1 | |
| SCHEMBL1796631 | 0.88 | TSHR (0.61) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635437-A1 | POLYMERIC FILMS AND METHODS TO MANUFACTURE THE SAME | ExxonMobil Chemical Patents Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012058789-A1 | POLYMERIC FILMS AND METHODS TO MANUFACTURE THE SAME | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-05-10 | — | — | WO | disclosed |