Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.66 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.64 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.56 |
| ▸ | ROS1 | P08922 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30223016 | 1.00 | EGFR (0.66) | EGFRMAPK3ALKROS1LRRK2 | |
| SCHEMBL23255650 | 0.94 | EGFR (0.64) | EGFRMAPK3LRRK2 | |
| SCHEMBL27238033 | 0.88 | EGFR (0.66) | EGFRMAPK3ALKROS1 | |
| SCHEMBL30223094 | 0.88 | EGFR (0.66) | EGFRMAPK3ALKROS1 | |
| SCHEMBL16780966 | 0.88 | ALK (0.66) | EGFRALK | |
| SCHEMBL27238037 | 0.88 | EGFR (0.66) | EGFRMAPK3ALKROS1 | |
| SCHEMBL30223472 | 0.88 | EGFR (0.66) | EGFRMAPK3ALKROS1 | |
| SCHEMBL23248539 | 0.87 | MAPK3 (0.68) | EGFRMAPK3ALKROS1 | |
| SCHEMBL16781051 | 0.87 | ALK (0.66) | EGFRALK | |
| SCHEMBL23248569 | 0.86 | EGFR (0.56) | EGFRMAPK3ALKROS1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4382514-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2024-06-12 | — | — | EP | disclosed |