Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19424572 | 0.95 | BCL2 (0.91) | BCL2 | |
| SCHEMBL1700602 | 0.94 | BCL2 (0.78) | BCL2 | |
| SCHEMBL19419635 | 0.92 | BCL2 (0.93) | BCL2 | |
| SCHEMBL1701741 | 0.91 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1701500 | 0.91 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1701498 | 0.91 | BCL2 (1.00) | BCL2 | |
| SCHEMBL30313995 | 0.91 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1701665 | 0.91 | BCL2 (1.00) | BCL2 | |
| SCHEMBL30313895 | 0.91 | BCL2 (1.00) | BCL2 | |
| SCHEMBL30314147 | 0.90 | BCL2 (1.00) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632436-A1 | SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT | Abbvie Inc. (US) | 2013-09-04 | — | — | EP | disclosed |
| EP-2613769-A1 | MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT | Abbvie Inc. (US) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012121758-A1 | MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT | ABBVIE INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012058392-A1 | SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT | ABBOTT LABORATORIES (US) | 2012-05-03 | — | — | WO | disclosed |