⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512636 | 0.71 | — | — | |
| SCHEMBL6566354 | 0.70 | — | — | |
| SCHEMBL10382153 | 0.68 | — | — | |
| SCHEMBL28963232 | 0.67 | — | — | |
| SCHEMBL5609556 | 0.67 | — | — | |
| SCHEMBL2283816 | 0.67 | — | — | |
| SCHEMBL2878964 | 0.67 | — | — | |
| SCHEMBL9935103 | 0.66 | — | — | |
| SCHEMBL14996909 | 0.66 | — | — | |
| SCHEMBL30732609 | 0.66 | NPSR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210071181-A1 | PHARMACEUTICAL COMPOSITION | ROCHE INNOVATION CT COPENHAGEN AS (DK) | 2021-03-11 | — | — | US | disclosed |
| EP-3372684-B1 | SINGLE-STRANDED RNAI AGENTS CONTAINING AN INTERNAL, NON-NUCLEIC ACID SPACER | SIRNA THERAPEUTICS INC (US) | 2020-10-07 | — | — | EP | disclosed |
| US-10584335-B2 | Single-stranded RNAi agents containing an internal, non-nucleic acid spacer | SIRNA THERAPEUTICS, INC. (US) | 2020-03-10 | — | — | US | disclosed |
| EP-3502255-A1 | PHARMACEUTICAL COMPOSITION | Roche Innovation Center Copenhagen A/S (DK) | 2019-06-26 | — | — | EP | disclosed |
| US-20190071672-A1 | Pharmaceutical Composition | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2019-03-07 | — | — | US | disclosed |
| EP-3431602-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ANTI-MIRNA ANTISENSE OLIGONUCLEOTIDES | Roche Innovation Center Copenhagen A/S (DK) | 2019-01-23 | — | — | EP | disclosed |
| EP-2666859-B1 | PHARMACEUTICAL COMPOSITION COMPRISING ANTI-MIRNA ANTISENSE OLIGONUCLEOTIDES | ROCHE INNOVATION CT COPENHAGEN AS (DK) | 2019-01-02 | — | — | EP | disclosed |
| EP-3372684-A1 | SINGLE-STRANDED RNAI AGENTS CONTAINING AN INTERNAL, NON-NUCLEIC ACID SPACER | Sirna Therapeutics, Inc. (US) | 2018-09-12 | — | — | EP | disclosed |
| US-20180195062-A1 | Pharmaceutical Composition | SANTARIS PHARMA A/S (DK) | 2018-07-12 | — | — | US | disclosed |
| US-20180112216-A1 | SEGMENTED MICRO RNA MIMETICS | BANK OF AMERICA, N.A. | 2018-04-26 | — | — | US | disclosed |
| WO-2004069990-A2 | OLIGOMERIC COMPOUNDS FOR THE MODULATION OF THIOREDOXIN EXPRESSION | SANTARIS PHARMA A/S (DK) | 2004-08-19 | — | — | WO | disclosed |
| US-20040106070-A1 | Method to enhance resolution of a chemically amplified photoresist | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2004-06-03 | — | — | US | disclosed |
| US-20040096848-A1 | Oligomeric compounds for the modulation HIF-1alpha expression | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2004-05-20 | — | — | US | disclosed |
| WO-2003085110-A2 | OLIGOMERIC COMPOUNDS FOR THE MODULATION HIF-1ALPHA EXPRESSION | SANTARIS PHARMA A/S (DK) | 2003-10-16 | — | — | WO | disclosed |
| US-6534243-B1 | A coating containing a cleaving compound to trim resist features; permitting a deprotection region to form within an inner portion of the patterned resist; removing coating and deprotection region to provide a second patterned feature | ADVANCED MICRO DEVICES, INC. | 2003-03-18 | — | — | US | disclosed |
| US-6492075-B1 | COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST | ADVANCED MICRO DEVICES, INC. | 2002-12-10 | — | — | US | disclosed |
| US-6274289-B1 | Chemical resist thickness reduction process | ADVANCED MICRO DEVICES, INC. | 2001-08-14 | — | — | US | disclosed |
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5847218-A | Sulfonium salts and chemically amplified positive resist compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |