⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21825490 | 0.87 | — | — | |
| SCHEMBL15288478 | 0.81 | — | — | |
| SCHEMBL4565937 | 0.79 | — | — | |
| SCHEMBL4978101 | 0.75 | CHRM2 (0.32) | — | |
| SCHEMBL22770535 | 0.75 | — | — | |
| SCHEMBL4975042 | 0.75 | — | — | |
| SCHEMBL2887784 | 0.75 | CHRM2 (0.30) | — | |
| SCHEMBL17393540 | 0.73 | — | — | |
| SCHEMBL20544034 | 0.73 | — | — | |
| SCHEMBL17113528 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199630-A1 | IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF | Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO) (ES) | 2024-06-20 | — | — | US | disclosed |
| EP-4063370-A1 | IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF | Fundación Centro Nacional de Investigaciones Oncológicas Carlos III (ES) | 2022-09-28 | — | — | EP | disclosed |