SCHEMBL2724554

SCHEMBL2724554

O=c1ccn([C@@H]2O[C@H](COOI)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.69
SLC28A2 O43868 1/20 0.69
SLC29A1 Q99808 1/20 0.69
SLC28A3 Q9HAS3 1/20 0.69
P2RY6 Q15077 8/20 0.67
P2RY2 P41231 12/20 0.65
P2RY4 P51582 5/20 0.65
P2RY14 Q15391 6/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1054387 0.90 SLC28A1 (0.72) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2168191 0.89 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2444841 0.89 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2552454 0.88 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2635506 0.88 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL24211446 0.88 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL15226209 0.88 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL4948478 0.88 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL17745011 0.87 SLC28A1 (0.67) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL4415327 0.87 SLC28A1 (0.67) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131305-A1 COMBINATION OF PRMT5 INHIBITOR AND ANTI-CANCER THERAPEUTIC AGENT 江苏先声药业有限公司 2023-07-13 WO claimed
EP-0197718-B2 New medicaments for topical use FIDIA SPA (IT) 2001-07-25 EP claimed
EP-0197718-B1 New medicaments for topical use FIDIA SPA (IT) 1993-12-15 EP claimed
US-4736024-A Process for preparing salt of hyaluronic acid with a pharmaceutically active substance FIDIA, S.P.A. (IT) 1988-04-05 US claimed
EP-0197718-A2 New medicaments for topical use FIDIA S.p.A. (IT) 1986-10-15 EP claimed
US-20130294576-A1 MONOCHROMATIC X-RAY DEVICES AND METHODS OF USE PRADHAN ANIL K (US) 2013-11-07 US disclosed
WO-2012054471-A1 MONOCHROMATIC X-RAY DEVICES AND METHODS OF USE THE OHIO STATE UNIVERSITY (US) 2012-04-26 WO disclosed