Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.62 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298203 | 0.87 | CHRM2 (0.79) | MEN1KMT2ACYP2C19ALDH1A1HTT | |
| SCHEMBL10728536 | 0.84 | CYP2C19 (0.69) | MEN1KMT2ACYP2C19ALDH1A1HTT | |
| SCHEMBL10350389 | 0.82 | MEN1 (0.69) | MEN1KMT2ACYP2C19ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL10350365 | 0.81 | MEN1 (0.68) | MEN1KMT2ACYP2C19ALDH1A1HTT | |
| SCHEMBL20595548 | 0.81 | CHRM2 (0.70) | MEN1KMT2ACYP2C19ALDH1A1HTT | |
| SCHEMBL30573473 | 0.81 | CHRM2 (0.70) | MEN1KMT2ACYP2C19ALDH1A1HTT | |
| Trimetazidine SCHEMBL2323475 | 0.81 | CYP1A2 (0.78) | MEN1KMT2ACYP2C19ALDH1A1HTT | |
| SCHEMBL30573474 | 0.80 | CYP2C19 (0.67) | MEN1KMT2ACYP2C19ALDH1A1HTT | |
| SCHEMBL29639701 | 0.80 | CYP2C19 (0.74) | MEN1KMT2ACYP2C19ALDH1A1HTT | |
| SCHEMBL9154432 | 0.80 | CYP2C19 (0.74) | MEN1KMT2ACYP2C19ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235297-A1 | COMPOUNDS AND METHODS FOR INCREASING EFFICIENCY OF CARDIAC METABOLISM | IMBRIA PHARMACEUTICALS, INC. (US) | 2023-12-07 | — | — | WO | disclosed |