SCHEMBL27254751

SCHEMBL27254751

CNc1ccc(-n2ccn(-c3c4c(nn3-c3cc(C)c(F)c(C)c3)CCN(C(=O)c3cc5ccccc5[nH]3)C4)c2=O)c(F)c1C=N

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 19/20 0.38
▸ MAPK14 Q16539 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22909448 0.83 GLP1R (0.47) GLP1R
SCHEMBL27254449 0.81 GLP1R (0.33) GLP1R
SCHEMBL22909743 0.80 GLP1R (0.47) GLP1RMAPK14
SCHEMBL22909275 0.79 GLP1R (0.57) GLP1R
SCHEMBL27254738 0.77 GLP1R (0.30) GLP1R
SCHEMBL22909616 0.77 GLP1R (0.52) GLP1R
SCHEMBL21203773 0.76 GLP1R (0.52) GLP1R
SCHEMBL27254842 0.75 GLP1R (0.58) GLP1R
SCHEMBL22909672 0.75 GLP1R (0.59) GLP1R
SCHEMBL23748748 0.73 GLP1R (0.54) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137426-A1 PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR ELI LILLY AND COMPANY (US) 2024-06-27 — — WO disclosed
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