SCHEMBL27255286

SCHEMBL27255286

c1ccc(-c2ccc(-c3cc(-c4ccccc4)nc(-c4ccc(-c5cccc(-c6ccc7sc8ccccc8c7c6)c5)c5ccccc45)n3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM3 Q86V86 1/20 0.41
ROCK1 Q13464 1/20 0.38
MEN1 O00255 6/20 0.37
KMT2A Q03164 6/20 0.37
MAPT P10636 4/20 0.37
ALDH1A1 P00352 4/20 0.37
HPGD P15428 4/20 0.37
LIMK1 P53667 1/20 0.37
NTSR1 P30989 1/20 0.37
ALOX5 P09917 1/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
GLA P06280 1/20 0.36
GPR3 P46089 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAP3K8 P41279 3/20 0.36
DHODH Q02127 1/20 0.35
TSHR P16473 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27255284 0.95 PIM3 (0.43) PIM3ROCK1MEN1KMT2AMAPT
SCHEMBL20706062 0.95 PIM3 (0.43) PIM3ROCK1MEN1KMT2AMAPT
SCHEMBL15501586 0.92 PIM3 (0.43) PIM3ROCK1MEN1KMT2AMAPT
SCHEMBL15501696 0.91 PIM3 (0.42) PIM3ROCK1MEN1KMT2AMAPT
SCHEMBL24343363 0.90 PIM3 (0.41) PIM3ROCK1MEN1KMT2AMAPT
SCHEMBL15501321 0.88 MEN1 (0.48) PIM3ROCK1MEN1KMT2AMAPT
SCHEMBL15501464 0.88 MEN1 (0.43) PIM3ROCK1MEN1KMT2AMAPT
SCHEMBL15501518 0.88 PIM3 (0.38) PIM3ROCK1MEN1KMT2AMAPT
SCHEMBL27390340 0.88 MEN1 (0.40) PIM3ROCK1MEN1KMT2AMAPT
SCHEMBL15501438 0.87 MEN1 (0.43) PIM3ROCK1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024024726-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2024-02-01 WO disclosed