Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.67 |
| ▸ | BCL2L1 | Q07817 | 11/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29796318 | 1.00 | BCL2 (0.67) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL2724329 | 0.96 | BCL2 (0.72) | BCL2BCL2L1 | |
| SCHEMBL29657423 | 0.96 | BCL2 (0.72) | BCL2BCL2L1 | |
| SCHEMBL30314016 | 0.96 | BCL2 (0.66) | BCL2BCL2L1 | |
| SCHEMBL29796316 | 0.95 | BCL2 (0.67) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL29657371 | 0.95 | BCL2 (0.67) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL2725532 | 0.94 | BCL2 (0.65) | BCL2BCL2L1 | |
| SCHEMBL29657428 | 0.94 | BCL2 (0.65) | BCL2BCL2L1 | |
| SCHEMBL30313826 | 0.92 | BCL2 (0.68) | BCL2BCL2L1 | |
| SCHEMBL30313869 | 0.92 | BCL2 (0.64) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435432-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2012-04-04 | — | — | EP | claimed |
| WO-2010138588-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | claimed |