Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870158 | 0.89 | BCL2 (0.45) | BCL2BCL2L1 | |
| SCHEMBL2724230 | 0.87 | BCL2 (0.47) | BCL2BCL2L1 | |
| SCHEMBL2725535 | 0.87 | BCL2 (0.49) | BCL2BCL2L1 | |
| SCHEMBL2724020 | 0.87 | BCL2 (0.45) | BCL2BCL2L1 | |
| SCHEMBL30622019 | 0.87 | BCL2 (0.50) | BCL2BCL2L1 | |
| SCHEMBL1871425 | 0.87 | BCL2 (0.50) | BCL2BCL2L1 | |
| SCHEMBL2725668 | 0.87 | BCL2 (0.51) | BCL2BCL2L1 | |
| SCHEMBL30622021 | 0.86 | BCL2 (0.49) | BCL2BCL2L1 | |
| SCHEMBL2724331 | 0.86 | BCL2 (0.55) | BCL2BCL2L1 | |
| SCHEMBL2723940 | 0.86 | BCL2 (0.49) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435432-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2012-04-04 | — | — | EP | claimed |
| WO-2010138588-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | claimed |