Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 2/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464569 | 1.00 | CPT1A (0.41) | CPT1ACPT2CPT1BHSP90AA1HSP90AB1 | |
| SCHEMBL6466400 | 0.89 | TRPV1 (0.39) | CPT1ACPT2CPT1BPOLBTRPV1 | |
| SCHEMBL2726110 | 0.89 | TRPV1 (0.39) | CPT1ACPT2CPT1BPOLBTRPV1 | |
| SCHEMBL2726881 | 0.89 | CPT2 (0.41) | CPT1ACPT2CPT1BHSP90AA1HSP90AB1 | |
| SCHEMBL10290107 | 0.89 | CPT2 (0.41) | CPT1ACPT2CPT1BHSP90AA1HSP90AB1 | |
| SCHEMBL2725418 | 0.88 | CPT2 (0.42) | CPT1ACPT2CPT1BHSP90AA1HSP90AB1 | |
| SCHEMBL6466478 | 0.88 | CPT2 (0.40) | CPT1ACPT2CPT1BHSP90AA1HSP90AB1 | |
| SCHEMBL2726984 | 0.87 | CPT2 (0.41) | CPT1ACPT2CPT1BHSP90AA1HSP90AB1 | |
| SCHEMBL2726932 | 0.85 | CPT2 (0.45) | CPT1ACPT2CPT1BHSP90AA1HSP90AB1 | |
| SCHEMBL6468193 | 0.85 | CPT1A (0.40) | CPT1ACPT2CPT1BHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |