SCHEMBL27264641

SCHEMBL27264641

Fc1ccc(-c2ocnc2P)cc1

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 17/20 0.54
NOTUM Q6P988 1/20 0.41
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
NR3C2 P08235 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472455 0.76 MAPK14 (0.54) MAPK14NOTUMNPC1RAB9A
SCHEMBL27252608 0.76 MAPK14 (0.54) MAPK14NOTUMNPC1RAB9ANR3C2
SCHEMBL27398917 0.76 MAPK14 (0.54) MAPK14NOTUMNPC1RAB9ANR3C2
SCHEMBL15947016 0.72 MAPK14 (0.50) MAPK14NOTUM
SCHEMBL2778903 0.72 MAPK14 (0.73) MAPK14NR3C2
SCHEMBL4470256 0.71 MAPK14 (1.00) MAPK14NR3C2
SCHEMBL1387433 0.71 MAPK14 (1.00) MAPK14NR3C2
SCHEMBL17746046 0.67 MAPK14 (0.45) MAPK14NOTUMNR3C2
SCHEMBL9248065 0.65 MAPK14 (0.61) MAPK14
SCHEMBL6751383 0.65 MAPK14 (0.57) MAPK14NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024059845-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-21 WO disclosed