Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.41 |
| ▸ | PDE2A | O00408 | 4/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30939011 | 0.90 | MAOB (0.54) | MAOBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13306474 | 0.81 | CA12 (0.51) | MAOBPDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL30919751 | 0.79 | MAPT (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7402911 | 0.77 | MAOB (0.57) | MAOBLMNAPDE3BPDE3APDE2A | |
| SCHEMBL31601553 | 0.76 | MAOB (0.56) | MAOBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30952863 | 0.76 | DDB1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL25206674 | 0.74 | PTPN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12321246 | 0.74 | MAOB (0.57) | MAOBLMNAPDE3BPDE3APDE2A | |
| SCHEMBL25318291 | 0.74 | MAOB (0.57) | MAOBLMNAPDE3BPDE3APDE2A | |
| SCHEMBL25921785 | 0.74 | MAOB (0.57) | MAOBLMNAPDE3BPDE3APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |