Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | CPT1A | P50416 | 8/20 | 0.36 |
| ▸ | CPT2 | P23786 | 7/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728954 | 0.94 | ACACB (0.38) | SMN1; SMN2TRPV1CPT1ACPT2PKM | |
| SCHEMBL2728191 | 0.92 | SMN1; SMN2 (0.38) | SMN1; SMN2TRPV1CPT1ACPT2PKM | |
| SCHEMBL10290682 | 0.91 | CPT1A (0.37) | SMN1; SMN2TRPV1CPT1ACPT2PKM | |
| SCHEMBL2710979 | 0.91 | CPT1A (0.37) | SMN1; SMN2TRPV1CPT1ACPT2PKM | |
| SCHEMBL2727845 | 0.90 | CPT1A (0.39) | SMN1; SMN2TRPV1CPT1ACPT2POLB | |
| SCHEMBL2727033 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2TRPV1CPT1ACPT2PKM | |
| SCHEMBL2726866 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2TRPV1CPT1ACPT2PKM | |
| SCHEMBL2728180 | 0.89 | HCRTR1 (0.38) | SMN1; SMN2TRPV1POLBHCRTR1HCRTR2 | |
| SCHEMBL2724978 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2TRPV1CPT1ACPT2POLB | |
| SCHEMBL2727131 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2TRPV1CPT1ACPT2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |