SCHEMBL27267136

SCHEMBL27267136

Pc1cccnc1-c1ccccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.57
KCNA5 P22460 3/20 0.46
S100A4 P26447 2/20 0.43
CDC25B P30305 1/20 0.43
LIMK1 P53667 1/20 0.42
PTPRC P08575 2/20 0.41
CTSL P07711 1/20 0.41
CTSS P25774 1/20 0.41
PTPN13 Q12923 1/20 0.41
TDP2 O95551 1/20 0.41
NSD2 O96028 1/20 0.41
ABL1 P00519 1/20 0.41
PLCG1 P19174 1/20 0.41
CES1 P23141 1/20 0.41
PAX8 Q06710 1/20 0.41
RIN1 Q13671 1/20 0.41
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20821396 0.84 DPP4 (0.65) DPP4KCNA5S100A4CDC25BLIMK1
SCHEMBL23630872 0.77 DPP4 (0.57) DPP4KCNA5S100A4CDC25BLIMK1
SCHEMBL1207550 0.77 DPP4 (0.57) DPP4KCNA5S100A4CDC25BLIMK1
SCHEMBL23636188 0.77 CYP2A6 (0.59) DPP4KCNA5S100A4CDC25BLIMK1
SCHEMBL9927285 0.76 TDP1 (0.44) S100A4CDC25BPTPRCCTSLCTSS
SCHEMBL27267792 0.76 DPP4 (0.47) DPP4KCNA5S100A4CDC25BLIMK1
SCHEMBL16047084 0.74 DPP4 (0.73) DPP4KCNA5S100A4CDC25BLIMK1
SCHEMBL17826981 0.73 DPP4 (0.71) DPP4KCNA5S100A4CDC25BLIMK1
SCHEMBL15674467 0.73 DPP4 (0.53) DPP4KCNA5LIMK1GAATP53
SCHEMBL6772449 0.73 DPP4 (0.53) DPP4KCNA5S100A4CDC25BLIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1019193-B Process for carbonylation of ethylenically unsaturated compounds with palladium catalyst SHELL INT RESEARCH (NL) 1992-11-25 CN disclosed
CN-88101206-A The method of the carbonylation of ethylenically unsaturated compounds under palladium catalyst 1988-09-28 CN disclosed