SCHEMBL27267629

SCHEMBL27267629

O=C(O)CCCCCCCNC(=O)COc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.73

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 7/20 0.73
▸ HDAC1 Q13547 6/20 0.73
▸ HDAC6 Q9UBN7 6/20 0.73
▸ HDAC3 O15379 2/20 0.73
▸ HDAC2 Q92769 2/20 0.73
▸ HDAC4 P56524 1/20 0.73
▸ NCOR2 Q9Y618 1/20 0.73
▸ DDB1 Q16531 5/20 0.73
▸ STAT3 P40763 2/20 0.69
▸ PIP4K2C Q8TBX8 2/20 0.60
▸ GSK3B P49841 2/20 0.57
▸ TRIM24 O15164 2/20 0.56
▸ BRD4 O60885 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29622167 1.00 CRBN (0.73) CRBNHDAC1HDAC6HDAC3HDAC2
SCHEMBL24376929 1.00 CRBN (0.73) CRBNHDAC1HDAC6HDAC3HDAC2
SCHEMBL29622144 1.00 CRBN (0.73) CRBNHDAC1HDAC6HDAC3HDAC2
SCHEMBL24558580 1.00 CRBN (0.73) CRBNHDAC1HDAC6HDAC3HDAC2
SCHEMBL22326312 1.00 CRBN (0.73) CRBNHDAC1HDAC6HDAC3HDAC2
SCHEMBL24765180 1.00 CRBN (0.73) CRBNHDAC1HDAC6HDAC3HDAC2
SCHEMBL23702529 0.99 CRBN (0.74) CRBNHDAC1HDAC6HDAC3HDAC2
SCHEMBL23636449 0.97 CRBN (0.75) CRBNHDAC1HDAC6HDAC3HDAC2
SCHEMBL26320196 0.94 STAT3 (0.76) CRBNHDAC1HDAC6HDAC3HDAC2
SCHEMBL25036554 0.94 CRBN (0.69) CRBNHDAC1HDAC6HDAC3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618755-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2025-09-24 — — EP disclosed
WO-2024107746-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES (US) 2024-05-23 — — WO disclosed
WO-2024107746-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES (US) 2024-05-23 — — WO disclosed
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