Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529232 | 0.77 | UHRF1 (0.41) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL23917887 | 0.74 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8MEN1 | |
| SCHEMBL3077708 | 0.71 | — | — | |
| SCHEMBL12501248 | 0.70 | NPC1 (0.39) | UHRF1CCR1CCR5CCR8MEN1 | |
| SCHEMBL1707627 | 0.70 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8MEN1 | |
| SCHEMBL23174775 | 0.69 | CCR1 (0.43) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL23174772 | 0.69 | CCR1 (0.43) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL29796503 | 0.69 | CCR1 (0.43) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL23174773 | 0.69 | CCR1 (0.43) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL29796494 | 0.69 | CCR1 (0.43) | FGFR1FGFR2FGFR4FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092115-A2 | MK2 INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-02 | — | — | WO | disclosed |