Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 11/20 | 0.50 |
| ▸ | ACE | P12821 | 11/20 | 0.50 |
| ▸ | CPA1 | P15085 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.45 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19042806 | 0.92 | MEN1 (0.59) | MMEMEN1KMT2ATAAR1EPHX1 | |
| SCHEMBL13827709 | 0.92 | MEN1 (0.59) | MMEMEN1KMT2ATAAR1EPHX1 | |
| SCHEMBL24306612 | 0.87 | MME (0.57) | MMEACE2ACECPA1EPHX1 | |
| SCHEMBL12524788 | 0.84 | ESR1 (0.51) | MMEACE2ACECPA1MEN1 | |
| SCHEMBL12829849 | 0.83 | SLC6A4 (0.41) | MEN1KMT2ATAAR1EPHX1MMP9 | |
| SCHEMBL14598295 | 0.82 | MME (0.54) | MMEACE2ACECPA1ACACB | |
| SCHEMBL20976910 | 0.82 | MME (0.54) | MMEACE2ACECPA1ACACB | |
| SCHEMBL8228374 | 0.82 | MME (0.54) | MMEACE2ACECPA1ACACB | |
| SCHEMBL15354984 | 0.80 | ITGB1 (0.49) | MMEACE2ACECPA1MEN1 | |
| SCHEMBL21263555 | 0.79 | MME (0.52) | MMEACE2ACECPA1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059472-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |