Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 14/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1872741 | 0.84 | BCL2 (0.47) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL2727829 | 0.84 | BCL2 (0.50) | BCL2BCL2L1 | |
| SCHEMBL2727181 | 0.84 | BCL2 (0.57) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL29657396 | 0.84 | BCL2 (0.57) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL2727456 | 0.83 | BCL2 (0.46) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL2726108 | 0.82 | BCL2 (0.44) | BCL2BCL2L1 | |
| SCHEMBL1873889 | 0.82 | BCL2 (0.50) | BCL2BCL2L1 | |
| SCHEMBL2723905 | 0.82 | BCL2 (0.48) | BCL2BCL2L1 | |
| SCHEMBL2707146 | 0.82 | BCL2 (0.52) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL1869290 | 0.82 | BCL2 (0.53) | BCL2BCL2L1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435432-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2012-04-04 | — | — | EP | claimed |
| WO-2010138588-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | claimed |