Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17303471 | 0.88 | HDAC1 (0.72) | HDAC1HDAC6MAPTGAAHTT | |
| SCHEMBL3584847 | 0.87 | HDAC1 (0.70) | HDAC1HDAC6MAPTGAAHTT | |
| SCHEMBL7081334 | 0.85 | HTT (0.60) | HDAC1HDAC6MAPTGAAHTT | |
| SCHEMBL4915929 | 0.85 | HDAC1 (0.68) | HDAC1HDAC6MAPTGAAHTT | |
| SCHEMBL17221212 | 0.85 | HDAC1 (0.68) | HDAC1HDAC6MAPTGAAHTT | |
| SCHEMBL24663640 | 0.84 | HDAC1 (0.67) | HDAC1HDAC6MAPTGAAHTT | |
| SCHEMBL30298601 | 0.83 | HDAC1 (0.65) | HDAC1HDAC6MAPTGAAHTT | |
| SCHEMBL12472822 | 0.83 | HDAC1 (1.00) | HDAC1HDAC6MAPTGAAHTT | |
| SCHEMBL3636330 | 0.81 | HDAC1 (0.68) | HDAC1HDAC6MAPTGAAHTT | |
| SCHEMBL15705714 | 0.81 | HDAC1 (0.76) | HDAC1HDAC6MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133560-A1 | IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS | DARK BLUE THERAPEUTICS LTD (GB) | 2024-06-27 | — | — | WO | disclosed |