Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515 | 0.91 | — | — | |
| SCHEMBL29273403 | 0.86 | — | — | |
| SCHEMBL28873736 | 0.86 | — | — | |
| SCHEMBL20636755 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL19459773 | 0.86 | — | — | |
| SCHEMBL29158323 | 0.86 | — | — | |
| SCHEMBL28549011 | 0.86 | — | — | |
| SCHEMBL29158409 | 0.86 | — | — | |
| Water SCHEMBL21612731 | 0.86 | TSHR (0.36) | TSHR | |
| SCHEMBL28912226 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101027279-B | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-03-27 | — | — | CN | claimed |
| CN-1980902-A | Method for preparing 5-'4-(2-hydroxy-propyl)-3,5-dioxo-4,5-dihydro-3h'1,2,4!triazin-2-yl!-benzamide derivatives by deprotecting the hydroxyl-protected precursers | PFIZER (US) | 2007-06-13 | — | — | CN | claimed |
| CN-1017991-B | Process for preparing 4-acetoxy-3-hydroxyethyl azetidin-2-one derivatives | KANEGAFUCHI CHEMICAL IND (JP) | 1992-08-26 | — | — | CN | claimed |
| CN-88100764-A | Process for preparing 4-acetoxy-3-hydroxyethyl azetidin-2-one derivatives | — | 1988-08-31 | — | — | CN | claimed |
| CN-104203950-A | Liver x receptor modulators | VITAE PHARMACEUTICALS INC | 2014-12-10 | — | — | CN | disclosed |
| CN-100354295-C | 2' -O-trisubstituted siloxymethyl-ribonucleoside derivatives and process for their preparation | NOVARTIS AG (CH) | 2007-12-12 | — | — | CN | disclosed |
| CN-1980902-A | Method for preparing 5-'4-(2-hydroxy-propyl)-3,5-dioxo-4,5-dihydro-3h'1,2,4!triazin-2-yl!-benzamide derivatives by deprotecting the hydroxyl-protected precursers | PFIZER (US) | 2007-06-13 | — | — | CN | disclosed |
| CN-1277828-C | Piperzine devivs. | HOFFMANN LA ROCHE (CH) | 2006-10-04 | — | — | CN | disclosed |
| CN-1738828-A | Avermectin b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4''- or 4'-position | SYNGENTA PARTICIPATIONS AG (CH) | 2006-02-22 | — | — | CN | disclosed |
| CN-1714097-A | 2' -O-trisubstituted siloxymethyl-ribonucleoside derivatives and process for their preparation | NOVARTIS AG (CH) | 2005-12-28 | — | — | CN | disclosed |
| CN-1649888-A | 4'-Deoxy-4'-(s)-amido avermectin derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2005-08-03 | — | — | CN | disclosed |
| CN-1608075-A | Avermectin b1 derivatives having an aminosulfonyloxy substitutent in the 4''-position | SYNGENTA PARTICIPATIONS AG (CH) | 2005-04-20 | — | — | CN | disclosed |
| CN-1549819-A | 4 '-deoxy-4' - (S) -amino avermectin derivatives | �����ɷ� | 2004-11-24 | — | — | CN | disclosed |
| CN-1452622-A | Piperzine devivs. | HOFFMANN LA ROCHE (CH) | 2003-10-29 | — | — | CN | disclosed |
| CN-1308071-A | Bicyclic DNA gyrase inhibitor | HOFFMANN LA ROCHE (CH) | 2001-08-15 | — | — | CN | disclosed |
| CN-1050829-C | Vitamin D compounds and method of preparing these compounds | DUPHAR INT RES (NL) | 2000-03-29 | — | — | CN | disclosed |
| CN-1114648-A | Novel monocyclic and bicyclic DNA gyrase inhibitors | HOFFMANN LA ROCHE (CH) | 1996-01-10 | — | — | CN | disclosed |
| CN-1099385-A | Vitamin D compounds and method of preparing these compounds | DUPHAR INT RES (NL) | 1995-03-01 | — | — | CN | disclosed |
| CN-1017991-B | Process for preparing 4-acetoxy-3-hydroxyethyl azetidin-2-one derivatives | KANEGAFUCHI CHEMICAL IND (JP) | 1992-08-26 | — | — | CN | disclosed |
| CN-88100764-A | Process for preparing 4-acetoxy-3-hydroxyethyl azetidin-2-one derivatives | — | 1988-08-31 | — | — | CN | disclosed |