Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.41 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | ATF1 | P18846 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690793 | 1.00 | MAP4K4 (0.43) | MAP4K4ARMAPKAPK2RORCNAMPT | |
| SCHEMBL23147917 | 0.86 | AR (0.43) | MAP4K4ARMAPKAPK2RORCNAMPT | |
| SCHEMBL29813534 | 0.85 | SYK (0.43) | MAP4K4ARMAPKAPK2RORCNAMPT | |
| SCHEMBL23147868 | 0.85 | SYK (0.43) | MAP4K4ARMAPKAPK2RORCNAMPT | |
| SCHEMBL29813512 | 0.84 | ATF1 (0.42) | MAP4K4ARMAPKAPK2RORCNAMPT | |
| SCHEMBL29813513 | 0.84 | ATF1 (0.42) | MAP4K4ARMAPKAPK2RORCNAMPT | |
| SCHEMBL23147986 | 0.84 | ATF1 (0.42) | MAP4K4ARMAPKAPK2RORCNAMPT | |
| SCHEMBL27280382 | 0.83 | MAP4K4 (0.44) | MAP4K4ARMAPKAPK2RORCNAMPT | |
| SCHEMBL30690681 | 0.83 | MAP4K4 (0.44) | MAP4K4ARMAPKAPK2RORCNAMPT | |
| SCHEMBL24551596 | 0.83 | MAPKAPK2 (0.49) | MAP4K4MAPKAPK2RORCNAMPTCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |