SCHEMBL27280604

SCHEMBL27280604

[N-]=[N+]=Nc1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.49
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
CA12 O43570 1/20 0.47
GABRA1 P14867 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
NPC1 O15118 4/20 0.46
ALDH1A1 P00352 4/20 0.46
RAB9A P51151 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
MAPK1 P28482 2/20 0.46
ELANE P08246 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28970715 0.98 CYP2C19 (0.51) CYP2C19CA1CA2CA9CA12
SCHEMBL21084970 0.76 CYP2C19 (0.54) CYP2C19NPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL14172627 0.75 CA1 (0.37) CA1CA2CA9CA12GABRA1
SCHEMBL13179763 0.75 CYP2C19 (0.57) CYP2C19NPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL17506045 0.75 CYP2C19 (0.53) CYP2C19NPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL14894920 0.74 CDC25B (0.48) CYP2C19CA1CA2CA9NPC1
SCHEMBL29420730 0.74 CDC25B (0.48) CYP2C19CA1CA2CA9NPC1
SCHEMBL13668026 0.73 CYP2C19 (0.56) CYP2C19NPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL10617594 0.73 CYP2C19 (0.51) CYP2C19NPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL10617590 0.73 CYP2C19 (0.51) CYP2C19NPC1ALDH1A1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed