Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24211525 | 0.78 | HTT (0.49) | GAAHTTKMT2ATHRBDYRK3 | |
| SCHEMBL2410520 | 0.78 | GAA (0.48) | GAAHTTKMT2ATHRBDYRK3 | |
| SCHEMBL2669892 | 0.77 | GAA (0.50) | GAAHTTKMT2ATHRBDYRK3 | |
| SCHEMBL22576451 | 0.76 | HTT (0.39) | GAAHTTDYRK1ALMNAALDH1A1 | |
| SCHEMBL26063963 | 0.74 | GAA (0.34) | GAAHTTKMT2ATHRBADORA3 | |
| SCHEMBL26063862 | 0.74 | GAA (0.34) | GAAHTTKMT2ATHRBDYRK3 | |
| SCHEMBL28019805 | 0.73 | NPC1 (0.51) | HTTKMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL2016297 | 0.73 | HTT (0.39) | GAAHTTKMT2ADYRK1AADORA3 | |
| SCHEMBL11190764 | 0.72 | GAA (0.43) | GAAHTTKMT2ATHRBDYRK3 | |
| SCHEMBL1437091 | 0.72 | GAA (0.43) | GAAHTTKMT2ATHRBDYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182737-B1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-07-03 | — | — | EP | disclosed |