⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517313 | 0.97 | SLC6A4 (0.41) | — | |
| Hydrochloric Acid SCHEMBL4811567 | 0.95 | SLC6A4 (0.39) | — | |
| SCHEMBL14043771 | 0.94 | — | — | |
| SCHEMBL9966034 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL15511667 | 0.86 | — | — | |
| SCHEMBL16373529 | 0.80 | KDM4E (0.33) | — | |
| SCHEMBL17780232 | 0.77 | KDM4E (0.38) | — | |
| SCHEMBL15001306 | 0.77 | — | — | |
| SCHEMBL9173934 | 0.75 | SOS1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL9177661 | 0.75 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388568-A1 | NLRP3 INHIBITORS | KODIAK SCIENCES INC (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4551549-A1 | NLRP3 INHIBITORS | Kodiak Sciences Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2024010772-A1 | NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-01-11 | — | — | WO | disclosed |