SCHEMBL27282

SCHEMBL27282

C/C=C(\Br)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27283 1.00
SCHEMBL29004152 0.74
SCHEMBL7780990 0.71
SCHEMBL10524387 0.71
SCHEMBL28519075 0.71
SCHEMBL1891164 0.71
SCHEMBL15338800 0.71
SCHEMBL7780988 0.71
SCHEMBL1891166 0.71
SCHEMBL10524391 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118719009-B Chromatography medium modification method 山东微领生物有限公司 2025-02-14 CN claimed
CN-118719009-A Novel chromatography medium modification method 山东微领生物有限公司 2024-10-01 CN claimed
US-20250179066-A1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2025-06-05 US disclosed
CN-118719009-B Chromatography medium modification method 山东微领生物有限公司 2025-02-14 CN disclosed
CN-118719009-A Novel chromatography medium modification method 山东微领生物有限公司 2024-10-01 CN disclosed
CN-110551069-B Synthesis method of 5-phenylpentanol compound and intermediate thereof 中国科学院上海有机化学研究所 2022-10-04 CN disclosed
US-20220281871-A1 Pyrazolo[1,5-A][1,3,5]Triazine and Pyrazolo[1,5-A]Pyrimidine Derivatives as CDK Inhibitors AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2022-09-08 US disclosed
EP-2508521-B2 Method for the production of amino crotonyl compounds BOEHRINGER INGELHEIM INT (DE) 2022-09-07 EP disclosed
EP-3981766-A1 INDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER Eisai R&D Management Co., Ltd. (JP) 2022-04-13 EP disclosed
US-10851065-B2 Tetrasubstituted alkene compounds and their use EISAI R&D MANAGEMENT CO., LTD. (JP) 2020-12-01 US disclosed
CN-105175331-B A kind of preparation method of the molecular targeted anti-tumor drug of EGFR class 江苏苏中药业集团股份有限公司 2019-04-26 CN disclosed
US-6379935-B1 USING MICROORGANISMS SHOWA DENKO KABUSHIKI KAISHA (JP) 2002-04-30 US disclosed
US-20020031811-A1 Method of producing alpha-halo-alpha, beta-saturated carbonyl compounds SHOWA DENKO K.K. 2002-03-14 US disclosed
US-20020028491-A1 METHOD OF PRODUCING ALPHA-HALO-ALPHA, BETA-SATURATED CARBONYL COMPOUNDS FROM THE CORRESPONDING ALPHA, BETA UNSURATED COMPOUNDS SHOWA DENKO KABUSHIKI KAISHA (JP) 2002-03-07 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
US-6184415-B1 ASYMMETRIC HYDROGENATION OF A 2-HALO(ELECTRONEGATIVE)ALKENOIC ACID/SALT (2-HALOACRYLIC ACID OR SALT), USING AN ENANTIOMETRICAL RICHED CATALYST OF 2,2'-BIS(DIARYLPHOSPHINO-PHINO-1,1'-BINAPHTHYL COMPLEX OF RUTHENIUM; HALIDE PROMOTERS ALBEMARLE CORPORATION 2001-02-06 US disclosed
EP-0979877-A2 Method of producing alpha-halo-alpha, beta-saturated carbonyl compounds SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-02-16 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-5717128-A HEATING AN ESTER OF 2-HYDROXY-2-METHYL-3-BUTENOIC ACID WITH PHOSPHOROUS BROMIDE OR CHLORIDE; THEN WITH TRIALKYL ESTER OF PHOSPHOROUS ACID BASF AKTIENGESELLSCHAFT (DE) 1998-02-10 US disclosed
US-H327-H Nematicidal alkenanilides FMC CORPORATION (US) 1987-09-01 US disclosed